Microgeography of staphyloccoci in human tissue explains antibiotic failure
Vishwachi Tripathi, Benedict Morin, Minia Antelo-Varela, Aline Amani Loriol, Kristiina Kurg, Sandro Jakonia, Asvin Ehsan, Sébastien Herbert, Alexia Ferrand, Loïc Sauteur, Florian C Marro, Noemi Henselmann, Jasmin Künnecke, Fabienne Estermann, Kerstin Strenger, , Dirk Bumann
The paper maps Staphylococcus aureus microgeography in human tissue using AI-guided imaging and finds antibiotic failure is linked to intracellular bacterial persistence and metabolic constraints.
bioRxiv · Sep 12, 2025 · PreprintMicrobiology