Opposing range-dependent interactions create complex spatial patterns of antibiotic tolerance in multispecies biofilms
Giulia Bottacin, Benjamin Raach, Leonard Fröhlich, Jasmin Künnecke, Andreas Kaczmarczyk, Alejandro Tejada-Arranz, Giovanni Stefano Ugolini, Roman Stocker, Urs Jenal, Dirk Bumann, Petra Stephanie Dittrich, Olga T. Schubert, Simon van Vliet
The paper shows that opposing range-dependent interactions between microbial exoproducts create complex spatial patterns of antibiotic tolerance in biofilms.
bioRxiv · Feb 6, 2026 · PreprintSystems Biology