Dirk Bumann

The paper identifies tRNA-modification requirements for bacterial virulence by analyzing codon usage in Salmonella and confirms their impact on gene expression and pathogenicity.

This study identifies Mnh1 as a key cation/proton antiporter promoting S. aureus phagocytic uptake and intracellular survival in human monocytes, suggesting it as a therapeutic target.

The paper shows that stress-adapted codon usage in Salmonella enhances virulence-gene expression under nutrient limitation and host-mimicking conditions.

This study shows S. aureus persists in musculoskeletal tissues despite antibiotic therapy, with residual bacteria capable of causing relapse.

The paper shows that opposing range-dependent interactions between microbial exoproducts create complex spatial patterns of antibiotic tolerance in biofilms.

This study shows that transient inhibition of T3SS-2 in Salmonella using doxycycline reduces virulence and disease symptoms, with long-term control similar to antibiotics.

The paper maps Staphylococcus aureus microgeography in human tissue using AI-guided imaging and finds antibiotic failure is linked to intracellular bacterial persistence and metabolic constraints.