ImmunologyJournal for ImmunoTherapy of CancerPeer-reviewed
TNFR2 blockade promotes anti-tumoral immune response in PDAC by targeting activated Treg and reducing T cell exhaustion
Anaïs Debesset, Caroline Pilon, Sylvain Meunier…·José Laurent Cohen
This study shows that blocking TNFR2 reduces Treg activity and T cell exhaustion in PDAC, with improved efficacy when combined with CD40 agonists.
29 citationstop 3%