Eliane Piaggio

This study shows that CBX3 deletion increases ROS and lipid ROS levels in CRC cells, sensitizing them to ferroptosis by disrupting the IFNγ/SLC7A11/SLC3A2 axis.

This study identifies altered follicular immunity and interferon hyperactivity in Down syndrome through single-cell and spatial profiling of human tonsils.

This study compares two humanized mouse models for cancer immunotherapies, finding differences in immune cell engraftment and tumor response to T-cell-directed therapies.

The paper identifies three CD8+ T cell subsets in ccRCC and links their differentiation states to clinical outcomes.

This study shows that poly(I:C) reprograms myeloid cells in rhabdoid tumors, enhancing CD8+ T cell infiltration and improving response to PD-1 blockade.

This study shows that combining PD-L1 and TIGIT blockade in a mouse model of rhabdoid tumors leads to tumor regression by promoting immune cell recruitment and vascular changes.

The paper identifies a common origin for effector and regulatory CD4+ T cells in non-small cell lung cancer through single-cell analysis, revealing their plasticity and role in immune responses.

This study shows that macrophages control collagen network topography via Tcf4-Collagen3 pathway, influencing immune cell infiltration in tumors.