Targeted therapy of oncomicrobe F. nucleatum with bioengineered probiotic expressing guided antimicrobial peptide (gAMP)
Ankan Choudhury, Colin Scano, Allison Barton, Christopher Michel Kearney, K. Leigh Greathouse
This paper develops a bioengineered probiotic expressing guided antimicrobial peptides to selectively target Fusobacterium nucleatum in colorectal cancer, showing reduced toxicity to non-target bacteria and preserved gut microbiota diversity.
Microbial Biotechnology · Dec 1, 2025Peer-reviewedMicrobiology