Colin Scano

This study identifies strain-specific virulence in Fusobacterium nucleatum and shows indole derivatives reduce invasion and alter junction transcripts in CRC cells.

This paper develops a bioengineered probiotic expressing guided antimicrobial peptides to selectively target Fusobacterium nucleatum in colorectal cancer, showing reduced toxicity to non-target bacteria and preserved gut microbiota diversity.

This study identifies coding and non-coding small RNAs in Bacteroides fragilis outer membrane vesicles that modulate inflammatory responses in intestinal epithelial cells, with ETBF OMVs showing immunosuppressive effects.