Canonical nuclear envelope protein emerin regulates structure and integrity of the erythrocyte plasma membrane
Brendan O'Brien, Joyleen Oliver, Evrett Thompson, Madeline Y. Mayday, Rubia Isler Mancuso, Alokkhumar Jha, Jennifer M. Kwan, Gisèle Bonne, Rabah Ben Yaou, France Leturcq, Suxia Bai, Timothy Nottoli, John Hwa, Diane S. Krause, Patrick G. Gallagher, , Kathleen A. Martin
This study shows emerin, a nuclear envelope protein, is expressed in red blood cells and regulates membrane structure and function, with mutations linked to RBC phenotypes like MCV.
bioRxiv · Jun 6, 2025 · PreprintCell Biology