Author

Alphonse de Koster

University of Amsterdam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Organism:Arabidopsis· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Benno H. ter KuileiD· 2 shared Martijs J. JonkeriD· 2 shared Xinyu Wang· 2 shared Belinda B. Koenders· 1 shared Gaurav DugariD· 1 shared Stanley BruliD· 1 shared Taichi CheniD· 1 shared Wim C. de LeeuwiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 22 mutual co-author links

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2 shared papersMicrobiology

Benno H. ter KuileORCID

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2 papers

Recent·Most cited

Modulation of rob expression accelerates development of antibiotic resistance in Yersinia enterocolitica

Xinyu Wang, Taichi Chen, Martijs J. Jonker, Alphonse de Koster, Wim C. de Leeuw, Benno H. ter Kuile, Gaurav Dugar

This study shows that overexpression of the Rob regulator in Yersinia enterocolitica accelerates antibiotic resistance development, but is costly without antibiotic selection.

Nucleic Acids Research · Jun 16, 2026Peer-reviewedMicrobiology

De novo acquisition of antibiotic resistance in six species of bacteria

Xinyu Wang, Alphonse de Koster, Belinda B. Koenders, Martijs J. Jonker, Stanley Brul, Benno H. ter Kuile

This study investigates de novo antibiotic resistance acquisition in six bacterial species, finding diverse mutational patterns leading to similar resistance outcomes.

Microbiology Spectrum · Feb 5, 2025Peer-reviewedMicrobiology