Bacterial and human exonucleases mediate interkingdom antiviral immunity
Courtney R Santos, Alyaa El-Guindy, Aaron Embry, Arabella E. Martin, Neal M. Alto, Don B. Gammon, Kevin J. Forsberg
This study identifies ISG20 and its bacterial homologs as interkingdom antiviral factors that restrict both bacterial RNA phages and human RNA viruses through UTR trimming.
bioRxiv · Jul 1, 2026 · PreprintMicrobiology