IRSp53 shapes the plasma membrane and controls polarized transport at the nascent lumen during epithelial morphogenesis
Sara Bisi, Abrar Rizvi, Stefano Marchesi, Davide Carra, Galina V. Beznoussenko, Ines Ferrara, Gianluca Deflorian, Mironov Aa, Giovanni Bertalot, Federica Pisati, Amanda Oldani, Angela Cattaneo, Salvatore Pece, Giuseppe Viale, Angela Bachi, , Andrea Disanza
This study identifies IRSp53's role in shaping the plasma membrane and controlling polarized transport during epithelial morphogenesis by regulating apical lumen formation and polarity determinants.
bioRxiv · Dec 3, 2019 · PreprintDevelopmental Biology