Author

Amber W. Wang

University of PennsylvaniaPrimary ORCID profile (0000-0001-5073-3980 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Amber W. WangiD2 papers · Brown University

Biology Disciplines

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Genetics· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:ATAC-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Klaus H. KaestneriD· 3 shared Adam M. ZahmiD· 2 shared Ashleigh R. Morgan· 2 shared Kirk J. WangensteeniD· 2 shared Yue Julia WangiD· 2 shared Andrew D. WellsiD· 1 shared Elisabetta ManduchiiD· 1 shared Eric L. WaiteiD· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenetics

Klaus H. KaestnerORCID

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3 papers

Recent·Most cited

Collapse of the hepatic gene regulatory network in the absence of FoxA factors

Yitzhak Reizel, Ashleigh R. Morgan, Long Gao, Yemin Lan, Elisabetta Manduchi, Eric L. Waite, Amber W. Wang, Andrew D. Wells, Klaus H. Kaestner

This study shows that FoxA factors are essential for maintaining the hepatic gene regulatory network in adult mice, as their loss leads to rapid hepatocyte dedifferentiation and lethality.

Genes & Development · Aug 1, 2020Peer-reviewedGenetics

The dynamic chromatin architecture of the regenerating liver

Amber W. Wang, Yue Julia Wang, Adam M. Zahm, Ashleigh R. Morgan, Kirk J. Wangensteen, Klaus H. Kaestner

The paper identifies CTCF and HNF4 as key regulators of hepatocyte proliferation and metabolic regulation during liver regeneration using ATAC-seq and ChIP-seq in a mouse model.

Cellular and Molecular Gastroenterology and Hepatology · Oct 17, 2019Peer-reviewedGenomics

A high-content in vivo screen to identify microRNA epistasis in the repopulating mouse liver

Adam M. Zahm, Amber W. Wang, Yue Julia Wang, Jonathan Schug, Kirk J. Wangensteen, Klaus H. Kaestner

The paper identifies miRNA epistasis in liver regeneration using a high-content in vivo screen in mice, revealing synergistic and redundant effects of miRNA interactions.

bioRxiv · Jun 11, 2019 · PreprintSystems Biology