Revealing the Grammar of Small RNA Secretion Using Interpretable Machine Learning
Bahar Zirak, Mohsen Naghipourfar, Ali Saberi, Delaram Pouyabahar, Amirhossein Zarezadeh, Lixi Luo, Lisa Fish, Doowon Huh, Albertas Navickas, Ali Sharifi‐Zarchi, Hani Goodarzi
This study introduces ExoGRU, a machine learning model that predicts small RNA secretion from sequence, identifies key RNA-binding proteins, and develops exoCLIP to map RNA interactomes in extracellular vesicles.
Cell Genomics · Mar 8, 2024Peer-reviewedSystems Biology