Author

Doowon Huh

Rockefeller UniversityORCID 0000-0003-2722-0217Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Hani GoodarziiD· 2 shared Lisa FishiD· 2 shared Albertas NavickasiD· 1 shared Alexandra M. PinzaruiD· 1 shared Ali Saberi· 1 shared Ali Sharifi‐ZarchiiD· 1 shared Amirhossein Zarezadeh· 1 shared Bahar Zirak· 1 shared

Activity by Year

2020-2024 · peak 1/yr

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10 top collaborators · 33 mutual co-author links

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2 shared papersSystems Biology

Hani GoodarziORCID

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2 papers

Recent·Most cited

Systems BiologyCell GenomicsPeer-reviewedMar 8, 2024

Revealing the Grammar of Small RNA Secretion Using Interpretable Machine Learning

Bahar Zirak, Mohsen Naghipourfar, Ali Saberi…·Hani Goodarzi

This study introduces ExoGRU, a machine learning model that predicts small RNA secretion from sequence, identifies key RNA-binding proteins, and develops exoCLIP to map RNA interactomes in extracellular vesicles.

8 citations

machine learning (classical)experimental assay

𝕏 PostBluesky

Molecular BiologyThe EMBO JournalPeer-reviewedDec 21, 2020

A stress-induced Tyrosine tRNA depletion response mediates codon-based translational repression and growth suppression

Doowon Huh, Maria C. Passarelli, Jenny Gao…·Sohail F. Tavazoie

The paper shows oxidative stress causes tyrosine tRNA fragmentation, leading to translational repression and growth suppression through depletion of the precursor tRNA and inhibition of transcript destabilization.

45 citations

humanC. elegans

𝕏 PostBluesky