BiochemistrybioRxivPreprint
A miniature CRISPR-Cas10 enzyme confers immunity by an inverse signaling pathway
Erin E. Doherty, Benjamin A. Adler, Peter H. Yoon…·Jennifer A. Doudna
The paper shows that the CRISPR-related enzyme mCpol produces cyclic oligonucleotides to prevent cell death and counteract viral immune evasion.