Author

Amrutha Pattamatta

University of Florida

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Eric T. WangiD· 1 shared Hailey R. Olafson· 1 shared J. Andrew BerglundiD· 1 shared Jared I. Richardson· 1 shared Laura P.W. RanumiD· 1 shared Lauren A. LaboissonniereiD· 1 shared Lien NguyeniD· 1 shared Marina M. Scotti· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Eric T. WangORCID

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1 paper

Recent·Most cited

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice

Amrutha Pattamatta, Lien Nguyen, Hailey R. Olafson, Marina M. Scotti, Lauren A. Laboissonniere, Jared I. Richardson, J. Andrew Berglund, Tao Zu, Eric T. Wang, Laura P.W. Ranum

This study shows longer G4C2 repeats in C9orf72 transgenic mice lead to earlier disease onset, higher penetrance, and more RNA foci, with alternative splicing changes as early biomarkers.

Human Molecular Genetics · Dec 15, 2020Peer-reviewedNeuroscience