Author

Lien Nguyen

University of FloridaORCID 0000-0001-5237-2576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Developmental Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Amrutha Pattamatta· 1 shared Andrea Suárez· 1 shared Ashakiran Rochette· 1 shared Eric T. WangiD· 1 shared Hailey R. Olafson· 1 shared Indu Tripathi· 1 shared J. Andrew BerglundiD· 1 shared Jacob A. BestiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Amrutha Pattamatta

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The fidelity of mRNA translation as a novel regulatory layer for brain development

Jacob A. Best, Pitchaporn Akaphan, Indu Tripathi, Ashakiran Rochette, Riku Nagai, Kryshna Miller, Andrea Suárez, Lien Nguyen, Kotaro Fujii

The paper shows translation fidelity varies across cell types and developmental stages, with brain and muscle having the highest accuracy, and demonstrates its role in neuronal differentiation.

bioRxiv · Apr 4, 2026 · PreprintDevelopmental Biology

Repeat length increases disease penetrance and severity in C9orf72 ALS/FTD BAC transgenic mice

Amrutha Pattamatta, Lien Nguyen, Hailey R. Olafson, Marina M. Scotti, Lauren A. Laboissonniere, Jared I. Richardson, J. Andrew Berglund, Tao Zu, Eric T. Wang, Laura P.W. Ranum

This study shows longer G4C2 repeats in C9orf72 transgenic mice lead to earlier disease onset, higher penetrance, and more RNA foci, with alternative splicing changes as early biomarkers.

Human Molecular Genetics · Dec 15, 2020Peer-reviewedNeuroscience