Regulatory start-stop elements in 5' untranslated regions pervasively modulate translation
Justin Rendleman, Solomon A. Haizel, Shaohuan Wu, Junjie Liu, Xinyi Ge, Huijing Zou, Mahabub Pasha Mohammad, Matthew Pressler, Shuvadeep Maity, Vladislava Hronová, Zhaofeng Gao, Anna Herrmannová, Amy Lei, Kristina Allgoewer, Daniel Sultanov, , Christine Vogel
The paper identifies start-stop elements in 5' UTRs that repress translation by halting ribosomes, showing their prevalence in human genes and impact on cellular processes.
bioRxiv · Jul 26, 2021 · PreprintSystems Biology