Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control
Anna M. Smirnova, Vladislava Hronová, Mahabub Pasha Mohammad…·Leoš Shivaya Valášek
The paper identifies a stem-loop and modified adenines in the uORF2/ATF4 overlap that regulate ATF4 translation under stress, revealing a more complex mechanism than previously thought.