Failure to resolve inflammation contributes to juvenile onset cardiac damage in a mouse model of Duchenne Muscular Dystrophy
James S. Novak, Amy Lischin, Prech Uapinyoying, Ravi Hindupur, Young Jae Moon, Surajit Bhattacharya, Sarah Tiufekchiev-Grieco, Victoria Barone, Davi A. G. Mázala, Iteoluwakishi H. Gamu, Gabriela Walters, Jyoti K. Jaiswal
This study shows that the D2-mdx mouse model exhibits juvenile-onset cardiac damage due to unresolved inflammation, and pro-resolution therapy can mitigate fibrotic degeneration.
Cell Death and Disease · Jul 9, 2025Peer-reviewedCell Biology