CD44 and Ezrin restrict EGF receptor mobility to generate a novel spatial arrangement of cytoskeletal signaling modules driving bleb-based migration
Ankita Jha, Ankit Chandra, Payam E. Farahani, Jared E. Toettcher, Ana M. Pasapera, Jason M. Haugh, Clare M. Waterman
The paper investigates how CD44 and Ezrin restrict EGF receptor mobility to create a spatial signaling gradient that stabilizes bleb-based migration in non-adhesive environments.
Nature Cell Biology · Jul 1, 2026Peer-reviewedCell Biology