Payam E. Farahani

The paper investigates how CD44 and Ezrin restrict EGF receptor mobility to create a spatial signaling gradient that stabilizes bleb-based migration in non-adhesive environments.

The paper develops a proximity mapping workflow to identify tumor-associated antigens by analyzing spatial protein communities and validates a TAA-TAPA pair that enhances tumor cell killing.

The paper uses pYtag biosensors to measure RTK activity in Drosophila, revealing feedback regulation that shapes developmental gradients.

This study uses light-controlled EGF receptors to precisely manipulate tissue movements in epithelial cells, showing light can drive millimeter-scale rearrangements.