Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P
Dieu-Huong Hoang, Jessica Bouvière, Johanna Galvis, Pauline Moullé, Orane Mercier, Eugenia Migliavacca, Ananga Ghosh, Gaëtan Juban, Sophie Liot, Pascal Stuelsatz, Fabien Le Grand, Jérôme N. Feige, Rémi Mounier, Bénédicte Chazaud
This study identifies that immune aging impairs muscle regeneration by altering macrophage-derived antioxidant selenoprotein P expression and function in aged mice.
EMBO Reports · Jul 18, 2025Peer-reviewedPhysiology