Author

Jérôme N. Feige

Nestlé (Switzerland)ORCID 0000-0002-4751-264XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Adrià GiliD· 1 shared Alessandra TammaroiD· 1 shared Ananga Ghosh· 1 shared Andrea Moran-CerroiD· 1 shared Ángel Sánchez-GonzáleziD· 1 shared Anne C. HespiD· 1 shared Araceli del ArcoiD· 1 shared Bénédicte ChazaudiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

Adrià GilORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-throughput screen identifies a potent MCU activator boosting cardiac contractile bioenergetics

Elena Caldero-Escudero, Marilén Federico, Ángel Sánchez-González, Adrià Gil, Silvia Fernandez‐Martinez, Paloma García-Casas, Rosalba I. Fonteríz, Flavien Bermont, Benjamin Brinon, Silvia Romero-Sanz, Andrea Moran-Cerro, Luis González-Moreno, Araceli del Arco, Shey‐Shing Sheu, Jérôme N. Feige, , Jaime Santo Domingo

The paper identifies CGP7930 as a potent MCU activator that enhances cardiac contractile bioenergetics through MICU1-dependent mechanisms.

bioRxiv · Sep 9, 2026 · PreprintBiochemistry

Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P

Dieu-Huong Hoang, Jessica Bouvière, Johanna Galvis, Pauline Moullé, Orane Mercier, Eugenia Migliavacca, Ananga Ghosh, Gaëtan Juban, Sophie Liot, Pascal Stuelsatz, Fabien Le Grand, Jérôme N. Feige, Rémi Mounier, Bénédicte Chazaud

This study identifies that immune aging impairs muscle regeneration by altering macrophage-derived antioxidant selenoprotein P expression and function in aged mice.

EMBO Reports · Jul 18, 2025Peer-reviewedPhysiology

NNMT promotes tubular senescence and fibrosis in chronic kidney disease

Lucie Chanvillard, Hildo C. Lantermans, Christopher Wall, Jonathan Thévenet, Loes M. Butter, Loic Tauzin, Nike Claessen, Stefan Christen, Sonia Karaz, Steve Lassueur, Giulia Lizzo, José Luis Sanchez-Garcia, Sylviane Métairon, James A. Holzwarth, Valentina Ferro, , Alessandra Tammaro

This study identifies NNMT as a driver of tubular senescence and fibrosis in CKD, showing its association with senescence markers and protective effects when inhibited.

bioRxiv · Jan 6, 2025 · PreprintCell Biology