Natural Selection has Shaped Coding and Non-coding Transcription in Primate CD4+ T-cells
Charles G. Danko, Lauren A. Choate, Brooke A. Marks, Edward J. Rice, Zhong Wang, Tinyi Chu, Andre L. Martins, Noah Dukler, Scott Alexander Coonrod, Elia D. Tait Wojno, John T. Lis, W. Lee Kraus, Adam C. Siepel
The paper compares nascent transcription in primates to identify evolutionary patterns in coding and non-coding transcription, finding that transcription factor binding sites and adaptive substitutions drive species-specific differences.
Nature Ecology & Evolution · Jan 27, 2018Peer-reviewedGenomics