Author

Andrea Comba

Primary ORCID profile (0000-0002-3398-5753 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Andrea CombaiD1 paper · University of Michigan

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anzar A. MujeebiD· 1 shared Ava Mauser· 1 shared Ayman Taher· 1 shared Brandon L. McClellaniD· 1 shared Claire E. TronrudiD· 1 shared Costas A. LyssiotisiD· 1 shared Felipe J NúñeziD· 1 shared Hanna S. HongiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anzar A. MujeebORCID

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1 paper

Recent·Most cited

Epigenetic reprogramming of autophagy leads to uncovering a novel therapeutic target for mutant IDH1 astrocytomas

Felipe J Núñez, Kaushik Banerjee, Anzar A. Mujeeb, Ava Mauser, Claire E. Tronrud, Ziwen Zhu, Sadhakshi Raghuram, Maya R. Sheth, Jorge Armando Pena Agudelo, Julio Zelaya, Ayman Taher, Padma Kadiyala, Stephen V. Carney, Maria B. Garcia-Fabiani, Andrea Comba, , Maria G. Castro

This study identifies autophagy as a critical survival pathway in mIDH1 gliomas and shows that inhibiting autophagy enhances radiosensitivity and tumor regression in preclinical models.

bioRxiv · Mar 8, 2024 · PreprintCancer Biology