Brandon L. McClellan

This study shows that combining CD73 inhibition with immune-stimulatory gene therapy improves treatment efficacy for wtIDH1 gliomas.

This study identifies MIF-CD74 axis regulation of myeloid cells in gliomas and shows that MIF inhibition enhances immune therapy efficacy in wtIDH1 gliomas.

This study shows that CD200 depletion in gliomas enhances antitumor immunity and leads to tumor rejection by modulating immune cell activity and cytokine expression.

This study identifies autophagy as a critical survival pathway in mIDH1 gliomas and shows that inhibiting autophagy enhances radiosensitivity and tumor regression in preclinical models.