Author

Andrew Day

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Organism:mouse· 1

Frequent Co-Authors

Adam Hunter· 2 shared Alexandra S. NeaversoniD· 2 shared Doreen N. PalsgroveiD· 2 shared Eleanor M. DowelliD· 2 shared Kaitlyn Walsh· 2 shared Malin H. L. AnderssoniD· 2 shared Matthew E. HurlesiD· 2 shared Minal J Patel· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersDevelopmental Biology

Adam Hunter

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Regulation and Function of the HPV16 CircE7 RNA

Eunice E. Lee, Yihui Huang, Eleanor M. Dowell, Kaitlyn Walsh, Calvin Hosler, Austin Witt, Odera Ifeacho, Doreen N. Palsgrove, Andrew Day, Claire D. James, Richard C. Wang

This study investigates the regulation and function of HPV16 circE7 RNA, showing that m6A modification and IRES-like motifs are critical for its formation and translation, impacting viral replication and transformation.

Journal of Virology · Sep 17, 2026Peer-reviewedMolecular Biology

Subclonal IDH1/2 Mutations as a Targetable Vulnerability in Vascular Tumors

Dong-Min Yu, E L Lee, Gabriel J. Starrett, Zili Zhai, Eleanor M. Dowell, Kaitlyn Walsh, Andrew Day, Doreen N. Palsgrove, Justin Bishop, Dylan M. Marchione, Maryam Asgari, Stephen S. Chung, W.L. High, Joyce M. C. Teng, Josh Wissell, , Richard C Wang

This study identifies low-variant allele frequency IDH1/2 mutations in sporadic angiosarcoma and shows they drive tumorigenesis through non-cell-autonomous mechanisms, responding to ivosidenib treatment.

bioRxiv · May 17, 2026 · PreprintCancer Biology

Differentiation of human induced pluripotent stem cells into cortical neural stem cells

Alexandra S. Neaverson, Malin H. L. Andersson, Osama A. Arshad, Luke Foulser, Mary Goodwin-Trotman, Adam Hunter, Ben Newman, Minal J Patel, Charlotte Roth, Tristan Thwaites, Helena Kilpinen, Matthew E. Hurles, Andrew Day, Sebastian S. Gerety

This paper describes a 14-day protocol to differentiate human iPSCs into cortical neural stem cells, validated through RNA-Seq and immunocytochemistry.

Frontiers in Cell and Developmental Biology · Jan 5, 2023Peer-reviewedDevelopmental Biology

Mouse and cellular models of KPTN-related disorder implicate mTOR signalling in cognitive and progressive overgrowth phenotypes

Maria O. Levitin, Lettie E. Rawlins, Gabriela Sánchez-Andrade, Osama A. Arshad, Stephan C. Collins, Stephen J. Sawiak, Philip H. Iffland, Malin H. L. Andersson, Caleb P. Bupp, Emma L. Cambridge, Eve L. Coomber, Ian Ellis, Johanna C. Herkert, Holly Ironfield, Logan Jory, , Sebastian S. Gerety

The paper investigates KPTN-related disorder using mouse and human stem cell models, identifying mTOR pathway dysregulation as a key mechanism underlying cognitive and overgrowth phenotypes.

bioRxiv · Jul 15, 2022 · PreprintGenetics