Author

Dylan M. Marchione

University of PennsylvaniaORCID 0000-0001-6941-0604Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew Day· 1 shared Benjamin A. GarciaiD· 1 shared Breelyn Wilky· 1 shared Carissa J. Lim· 1 shared Delaney K. FischeriD· 1 shared Donald Dlass· 1 shared Dong-Min Yu· 1 shared Doreen N. PalsgroveiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Andrew Day

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2 papers

Recent·Most cited

Subclonal IDH1/2 Mutations as a Targetable Vulnerability in Vascular Tumors

Dong-Min Yu, E L Lee, Gabriel J. Starrett, Zili Zhai, Eleanor M. Dowell, Kaitlyn Walsh, Andrew Day, Doreen N. Palsgrove, Justin Bishop, Dylan M. Marchione, Maryam Asgari, Stephen S. Chung, W.L. High, Joyce M. C. Teng, Josh Wissell, , Richard C Wang

This study identifies low-variant allele frequency IDH1/2 mutations in sporadic angiosarcoma and shows they drive tumorigenesis through non-cell-autonomous mechanisms, responding to ivosidenib treatment.

bioRxiv · May 17, 2026 · PreprintCancer Biology

Set2-mediated alternative splicing of Srsf11 regulates cocaine reward behavior

Song-Jun Xu, Sonia I Lombroso, Delaney K. Fischer, Marco D. Carpenter, Dylan M. Marchione, Peter J. Hamilton, Carissa J. Lim, Rachel L. Neve, Benjamin A. Garcia, Mathieu E. Wimmer, Robert Christopher Pierce, Elizabeth A. Heller

This study shows that Set2-mediated H3K36me3 regulates alternative splicing of Srsf11, which influences cocaine reward behavior in mice.

Neuron · Sep 1, 2021Peer-reviewedNeuroscience