Author

Andrew G. Duncan

University of Toronto

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Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan M MosesiD· 1 shared Gurdeep SinghiD· 1 shared Jennifer A. MitchelliD· 1 shared Richard ZhangiD· 1 shared Ruxiao Tian· 1 shared Sakthi D. MoorthyiD· 1 shared Shanelle Mullany· 1 shared Tahmid Mehdi· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

Alan M MosesORCID

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1 paper

Recent·Most cited

A flexible repertoire of transcription factor binding sites and diversity threshold determines enhancer activity in embryonic stem cells

Gurdeep Singh, Shanelle Mullany, Sakthi D. Moorthy, Richard Zhang, Tahmid Mehdi, Ruxiao Tian, Andrew G. Duncan, Alan M Moses, Jennifer A. Mitchell

The paper identifies a diversity threshold of transcription factor binding sites (TFBS) required for enhancer activity in embryonic stem cells, showing that a diverse set of TFBS can replace optimized regulatory sequences.

Genome Research · Apr 1, 2021Peer-reviewedGenomics