Gurdeep Singh

The paper uses hybrid RNA sequencing to analyze transcript isoform changes during influenza infection and interferon treatment, identifying RNA-binding proteins involved in immune remodeling.

This study identifies gene expression and signaling changes in the neurovascular unit following prenatal alcohol exposure across development.

This study shows that somatic copy number mutations (CNA) influence metastatic fitness in breast cancer by mediating transcriptional changes and affecting clone survival in different sites.

The paper identifies genomic and non-genomic contributions to drug resistance in triple negative breast cancer using single cell transcriptomics and copy number data.

The paper identifies a diversity threshold of transcription factor binding sites (TFBS) required for enhancer activity in embryonic stem cells, showing that a diverse set of TFBS can replace optimized regulatory sequences.

The paper introduces a semi-supervised clustering model for identifying active enhancers in mouse heart tissues using heterogeneous genomic data.