Author

Shanelle Mullany

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:DNA methylation· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Jennifer A. MitchelliD· 3 shared Sakthi D. MoorthyiD· 2 shared Tiegh Taylor· 2 shared Tom SextoniD· 2 shared Alan M MosesiD· 1 shared Alisha Suri· 1 shared Andrew G. Duncan· 1 shared Chenfan Ji· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMolecular Biology

Jennifer A. MitchellORCID

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Author profile →

3 papers

Recent·Most cited

Enhancers mediate euchromatin hopping at chromatin contact points

Shanelle Mullany, Tiegh Taylor, Hangpeng Li, Yaqing Zhao, Alisha Suri, Tom Sexton, James O. J. Davies, Jennifer A. Mitchell

The paper shows enhancers mediate euchromatin hopping, spreading euchromatin features to distal regions through chromatin looping, redefining enhancer identification using chromatin features.

bioRxiv · Sep 5, 2025 · PreprintMolecular Biology

Transcriptional regulation and chromatin architecture maintenance are decoupled modular functions at the Sox2 locus

Tiegh Taylor, Natalia Sikorska, Virlana M. Shchuka, Sanjay Chahar, Chenfan Ji, Neil N. Macpherson, Sakthi D. Moorthy, Marit A. C. de Kort, Shanelle Mullany, Nawrah Khader, Zoe E. Gillespie, Lida Langroudi, Ian C. Tobias, Tineke Laura Lenstra, Jennifer A. Mitchell, Tom Sexton

The paper shows that transcriptional control and chromatin architecture at the Sox2 locus are decoupled, with distinct regulatory mechanisms.

Genes & Development · Jun 1, 2022Peer-reviewedGenetics

A flexible repertoire of transcription factor binding sites and diversity threshold determines enhancer activity in embryonic stem cells

Gurdeep Singh, Shanelle Mullany, Sakthi D. Moorthy, Richard Zhang, Tahmid Mehdi, Ruxiao Tian, Andrew G. Duncan, Alan M Moses, Jennifer A. Mitchell

The paper identifies a diversity threshold of transcription factor binding sites (TFBS) required for enhancer activity in embryonic stem cells, showing that a diverse set of TFBS can replace optimized regulatory sequences.

Genome Research · Apr 1, 2021Peer-reviewedGenomics