Experimental Phage Evolution Results in Expanded Host Ranges Against MDR and XDR Klebsiella pneumoniae Isolates
Pooja Ghatbale, Alisha N. Blanc, Andrew D. Sue, Jesse Leonard, Monica Bates, Andrew G. Garcia, Joshua Hensley, Danielle Devequi Gomes Nunes, Nicole Hitchcock, Job Shiach, Roberto Bardaró, Govind Prasad Sah, Chandrabali Ghose, Katrine Whiteson, Robert Turner Schooley, , David T. Pride
The paper demonstrates that experimental phage evolution can expand the host range of phages to kill multidrug-resistant and extensively-drug-resistant Klebsiella pneumoniae isolates.
Nature Communications · Nov 19, 2025Peer-reviewedMicrobiology