Jyot D. Antani

SUN2 mediates epigenetic remodeling to drive mechanotransduction during skin fibrosis

This study identifies SUN2 as a mediator of nuclear mechanosensing in fibrosis, showing it drives chromatin remodeling and fibrotic gene expression in response to mechanical stiffness.

Prophage activity shapes the thermal ecology and evolution of a marine bacterial host

This study shows prophage infection influences bacterial thermal ecology and evolution by altering thermal adaptation and population dynamics across temperatures.

Flagellotropic bacteriophage selects for evolutionary remodeling of cell motility and chemotaxis in Escherichia coli

This study shows that phage resistance in E. coli leads to diverse single-cell motility outcomes and signaling pathway changes, revealing trade-offs and trade-ups in motility and chemotaxis.

Microscopic Phage Adsorption Assay: High-throughput quantification of virus particle attachment to host bacterial cells

This paper introduces a high-throughput method to quantify phage attachment to bacterial cells using fluorescence microscopy and particle tracking, revealing single-virus dynamics and enabling rapid screening.

Identification of a large cohort of Enterobacter jumbo phages with broad host ranges across pathogenic Gammaproteobacteria

The paper identifies eight Enterobacter jumbo phages with broad host ranges across pathogenic Gammaproteobacteria, suggesting potential as antibiotic alternatives.

Bacterial Receptors but Not Anti-Phage Defense Mechanisms Determine Host Range for a Pair of Pseudomonas aeruginosa Lytic Phages

The paper identifies bacterial receptor genes determining phage host range, showing defense mechanisms are not predictive of susceptibility.