Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity
Jonathan A. Kuhn, Parijat Banerjee, Andrew Haye, Douglas N. Robinson, Pablo A. Iglesias, Peter N. Devreotes
This study identifies cytoskeletal feedback loops that regulate Ras/PI3K signaling and cell polarity in Dictyostelium and neutrophils by modulating actin and myosin dynamics.
Nature Communications · Aug 12, 2025Peer-reviewedCell Biology