Exploring the deletion landscape of S. aureus Cas9 with SABER
Andrew J. Plebanek, Luke M. Oltrogge, Cynthia I. Terrace, Maria Lukarska, Maggie Khoury, David F. Savage
The paper introduces SABER, a method to efficiently map tolerated deletions in SaCas9, enabling the design of minimal CRISPRi effectors.
bioRxiv · Aug 12, 2025 · PreprintMolecular Biology