Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis
David Ellison, Andrew Mugler, Matthew Brennan, Sung Hoon Lee, Robert Huebner, Eliah Shamir, Laura A Woo, Joseph Kim, Patrick Amar, Ilya Nemenman, Andrew J Ewald, Andre Levchenko
The paper shows that cell-cell communication improves the ability of cell groups to detect weak chemical gradients, but this benefit is limited by signaling noise.
bioRxiv · Aug 23, 2015Biophysics