Development of a Time-based Drug Screening Platform for Improved Clinical Translation
Elizabeth A. Hughes, Lindsay L Davenport, Andrew Woodward, Shravan Patel, Jamie Lee, Christopher Zdyrski, Aleksandra Pawlak, Karin Allenspach, Jonathan Paul Mochel, Eugene F. Douglass
This paper develops a time-based drug screening platform to assess clinical utility by integrating pharmacokinetic-pharmacodynamic models and analyzing drug potency and kinetics in cancer cell lines.
bioRxiv · Oct 24, 2025 · PreprintPharmacology & Toxicology