Processive activity of the replicative DNA polymerases in the replisome of live eukaryotic cells
Nitin Kapadia, Ziad W. El‐Hajj, Huan Zheng, Thomas R. Beattie, Angela Yu, Rodrigo Reyes‐Lamothe
The paper uses single-molecule fluorescence microscopy to study replisome subunit dynamics in live yeast, showing long residence times and coordinated activity, redefining the replisome architecture.
Molecular Cell · Sep 10, 2020Peer-reviewedMolecular Biology