NeuroscienceNature Structural & Molecular BiologyPeer-reviewed
Repositioning of polyubiquitin alters the pathologic tau filament structure
Ryohei Watanabe, Benjamin C. Creekmore, Nabil F. Darwich…·Edward B. Lee
This study shows that polyubiquitin repositioning affects tau filament structure in tauopathies, altering their seeding activity in mice.
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