Ischemic injury triggers a protective microglial phenotype in models of Aβ pathology
Michael Candlish, Jan C. Hofmann, Desirée Brösamle, Annika Haessler, Murphy DeMeglio, Angelos Skodras, Georgi Tushev, Eloah S. De Biasi, Stefan Günther, René Wiegandt, Heidi Theis, Elena De Domenico, Nina Sofia Hermann, Peter Breunig, Christina Sauerland, , Jasmin K. Hefendehl
The paper investigates how ischemic injury affects microglial response to Aβ pathology, finding a protective microglial phenotype that promotes benign Aβ plaque formation.
Journal of Neuroinflammation · Jun 9, 2026Peer-reviewedNeuroscience