Author

Christina Sauerland

Goethe University Frankfurt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Jasmin K. HefendehliD· 3 shared Michael CandlishiD· 3 shared Peter BreunigiD· 3 shared Stefan GüntheriD· 3 shared Amparo Acker‐PalmeriD· 2 shared Angelos Skodras· 2 shared Eloah S. De Biasi· 2 shared Mario LoosoiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Jasmin K. HefendehlORCID

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Author profile →

3 papers

Recent·Most cited

Ischemic injury triggers a protective microglial phenotype in models of Aβ pathology

Michael Candlish, Jan C. Hofmann, Desirée Brösamle, Annika Haessler, Murphy DeMeglio, Angelos Skodras, Georgi Tushev, Eloah S. De Biasi, Stefan Günther, René Wiegandt, Heidi Theis, Elena De Domenico, Nina Sofia Hermann, Peter Breunig, Christina Sauerland, , Jasmin K. Hefendehl

The paper investigates how ischemic injury affects microglial response to Aβ pathology, finding a protective microglial phenotype that promotes benign Aβ plaque formation.

Journal of Neuroinflammation · Jun 9, 2026Peer-reviewedNeuroscience

Ischemic stroke induces persistent alteration to brain stromal progenitor cells linked to chronic vascular dysfunction

Michael Candlish, Peter Breunig, Işıl Özdemir, Christina Sauerland, Stefan Günther, Khrievono Kikhi, Mario Looso, Iman Ghasemi, Katrin Schäfer, Amparo Acker‐Palmer, Shamim Ashrafiyan, Johanna Ernst, Hans Worthmann, Gerrit Maximilian Große, T. Michael Underhill, , Jasmin K. Hefendehl

This study shows ischemic stroke causes long-term changes in brain stromal progenitor cells, leading to vascular dysfunction and potential recurrent stroke.

bioRxiv · Dec 12, 2025 · PreprintNeuroscience

Soluble epoxide hydrolase upregulation in Alzheimer's disease promotes blood-brain barrier dysfunction

Murphy DeMeglio, Eloah S. De Biasi, Peter Breunig, Michael Candlish, Christina Sauerland, Stefan Günther, Haruya Kawase, Blanca Peguera, Christine Bohnstaedt, Peter R. Nilsson, Jiong Hu, Susanne S. Hille, Oliver J Mueller, Amparo Acker‐Palmer, Bruce D. Hammock, , Jasmin K. Hefendehl

This study shows that soluble epoxide hydrolase in astrocytes contributes to vascular instability in Alzheimer's disease, and its deletion reduces vascular amyloid burden and preserves vascular structure.

bioRxiv · Dec 11, 2025 · PreprintNeuroscience