Author

Anika Alim

Binghamton University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Jungwook PaekiD· 4 shared Myungwoon LeeiD· 4 shared Yoongyeong Baek· 3 shared Purnopama Saha· 2 shared Sandra Lwin· 1 shared Tarek Olabi· 1 shared Teshani LiyanaarachchigeiD· 1 shared Yanheng Dong· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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4 shared papersMolecular Biology

Jungwook PaekORCID

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4 papers

Recent·Most cited

Aβ42-Driven α-synuclein Fibril Polymorphism and Distinct Intracellular Aggregation

Purnopama Saha, Teshani Liyanaarachchige, Anika Alim, Jungwook Paek, Myungwoon Lee

This study shows that Aβ42 monomers and preformed fibrils differentially affect α-synuclein fibril formation, structure, and neuronal toxicity.

bioRxiv · Sep 14, 2026 · PreprintMolecular Biology

Vascularizing neurospheroids to probe vascular contributions to α-synuclein pathology in Parkinson's disease

Anika Alim, Sandra Lwin, Purnopama Saha, Yoongyeong Baek, Myungwoon Lee, Jungwook Paek

This study develops a vascularized brain model to investigate how vascular dysfunction contributes to Parkinson's disease pathology by inducing α-synuclein aggregation in neurons.

bioRxiv · Aug 31, 2026 · PreprintBioengineering

Lipid Acyl Chain-Driven α-Synuclein Fibril Polymorphisms and Neuronal Pathologies

Yoongyeong Baek, Anika Alim, Yanheng Dong, Tarek Olabi, Jungwook Paek, Myungwoon Lee

This study shows that age-related membrane changes affect α-synuclein fibril structure and pathogenicity, linking membrane dynamics to neurodegeneration.

ACS Chemical Neuroscience · Mar 13, 2026Peer-reviewedMolecular Biology

Microphysiological engineering of the capillary interface of substantia nigra dopaminergic neurons to study vascular alterations in Parkinson's Disease

Anika Alim, Yoongyeong Baek, Myungwoon Lee, Jungwook Paek

This paper develops an organ-on-a-chip model of dopaminergic neurons and capillaries to study vascular changes in Parkinson's Disease.

bioRxiv · May 14, 2025 · PreprintBioengineering