Sleep-like state during wakefulness induced by psychedelic 5-MeO-DMT in mice
Benjamin J. B. Bréant, José Prius-Mengual, Anna Hoerder-Suabedissen, Jasmin Patel, David M. Bannerman, Trevor Sharp, Vladyslav V. Vyazovskiy
This study shows that 5-MeO-DMT induces a dissociated brain state in mice with features of both wakefulness and sleep, including slow waves and pupil dilation, while suppressing REM sleep.
bioRxiv · Dec 11, 2022 · PreprintNeuroscience