Vladyslav V. Vyazovskiy

The paper shows that manipulating cortical activity during sleep deprivation prevents ER stress responses while increasing sleep pressure markers.

This study examines brain-heart coordination during NREM sleep using EEG and ECG data, finding that SO-R-peak coupling and JPAC metrics track physiological states and correlate with autonomic markers.

This study shows that silencing layer 6b neurons in mice alters theta frequency and EEG power during wake and sleep, and reduces orexin-induced wakefulness.

The paper shows that sleep deprivation causes depolarizing GABAAR signaling and spike threshold adaptation in cortical neurons, stabilizing network activity despite increased firing rates.

This study shows that sleep after noise overexposure in mice increases tinnitus development, as measured by changes in GPIAS, while hearing loss remains unaffected.

The paper investigates EMG activity during daily torpor in Djungarian hamsters, finding periodic motility and brain activation linked to thermoregulation and vigilance.

This study investigates how global and local cortical activity affects sleep regulation using chemogenetic manipulations of Rbp4-Cre+ neurons.

This study shows that β2AR agonists enhance thermogenesis and prevent obesity by improving sympathetic neuron function in mice.

This study shows that a mutation in synaptobrevin 2 in mice leads to abnormal cortical activity patterns across sleep and wake states, resembling deep anaesthesia.

The paper investigates how micro-arousals affect neural activity in the motor cortex of sleep-deprived mice, finding increased slow wave activity immediately after micro-arousals.

This study examines how sleep state affects cortical evoked activity in ferrets with tinnitus, finding a link between tinnitus and sleep disruption, with neural markers of tinnitus reduced during sleep.

Somnotate is a probabilistic classifier that improves sleep stage annotation in mice by identifying intermediate states and transitions, outperforming human experts.

This study shows that diurnal changes in GABAA receptor equilibrium potential modulate glutamatergic long-term potentiation in mouse cortical neurons.

This study shows that ablating adult oligodendrogenesis alters brain microstructure and activity without affecting behaviour.

This study introduces a new metric, oscillatory Quality (o-Quality), to quantify sleep spindle oscillatory strength in mice and links it to functional roles in sleep.

The paper identifies low amplitude neural activity segments during NREM sleep as OFF periods, showing they have distinct characteristics and new properties like vigilance-state-dependent duration.

This study shows that clozapine-N-oxide and compound 21 affect sleep in mice, suggesting that chemogenetic actuators may have off-target effects beyond DREADD receptor activation.

This study shows that 5-MeO-DMT induces a dissociated brain state in mice with features of both wakefulness and sleep, including slow waves and pupil dilation, while suppressing REM sleep.

This paper develops a closed-loop stimulation method using neuronal spiking activity to detect ON and OFF states during slow oscillations in freely moving mice.

This study shows that SIK1 activity modulates synaptic phosphoproteome to induce sleep independently of sleep pressure, revealing a causal mechanism for sleep regulation.

This study shows that silencing specific cortical neurons in mice increases wakefulness and reduces sleep rebound after deprivation, highlighting the cortex's role in sleep regulation.

The paper shows that intraneuronal chloride levels increase with wakefulness, reducing synaptic inhibition and affecting cortical function, and that targeting chloride can restore performance in tired states.

This study investigates the relationship between fasting-induced torpor, sleep, and wakefulness in mice by analyzing EEG, EMG, and body temperature data.

This study shows that different types of waking experiences in mice affect sleep pressure differently, with task-based wakefulness reducing sleep need more than exploratory behavior.

This study shows psilocin disrupts sleep patterns and affects local but not global sleep homeostasis in mice, potentially linking to its antidepressant effects.

This study shows that hypothalamic stimulation increases cortical activity and accelerates sleep pressure buildup, indicating the hypothalamus regulates both state transitions and within-state arousal intensity.

This study identifies a Vamp2 mutation in mice that causes sleep-wake transition deficits by reducing synaptic release probability.

This study develops mathematical models of sleep homeostasis in mice, showing Process S integrates local cortical neuronal activity over time to regulate sleep quantity.