MapToCleave: high-throughput profiling of microRNA biogenesis in living cells
Wenjing Kang, Bastian Fromm, Anna J.S. Houben, Eirik Høye, Daniela Bezdan, Carme Arnan, Kim Thrane, Michaela Asp, Rory Johnson, Inna Biryukova, Marc R. Friedländer
The paper introduces MapToCleave, a method to profile miRNA biogenesis in living cells, showing that stable lower basal stems enhance processing and expression across species.
Cell Reports · Nov 1, 2021Peer-reviewedMolecular Biology