Kim Thrane

The paper uses spatial and single-cell techniques to show T and B cell clonal expansion in CXCL9-rich niches of sinonasal cancer, linking immune hubs to tumor regions.

The paper introduces SiT, a method to characterize spatial isoform variation and sequence heterogeneity in tissue sections, revealing regional isoform switching and RNA editing in mouse brain.

This paper introduces a method to combine histology and spatial gene expression data to infer high-resolution transcriptome maps without sequencing or hybridization.

The paper introduces MapToCleave, a method to profile miRNA biogenesis in living cells, showing that stable lower basal stems enhance processing and expression across species.

The paper uses spatial transcriptomics to analyze copy number variations in benign and malignant tissues, revealing clonal patterns and suggesting early cancer evolution mechanisms.