Leveraging biobank-scale rare and common variant analyses to identify ASPHD1 as the main driver of reproductive traits in the 16p11.2 locus
Katrin Männik, Thomas Arbogast, Maarja Lepamets, Kaido Lepik, Anna Pellaz, Herta Ademi, Zachary A Kupchinsky, Jacob Ellegood, Catia Attanasio, Andrea Messina, Samuel Rotman, Sandra Martin‐Brevet, Estelle Dubruc, Jacqueline Chrast, Jason P. Lerch, , Alexandre Reymond
The paper identifies ASPHD1 as a key driver of reproductive traits in the 16p11.2 locus using biobank data, Mendelian randomization, and animal models.
bioRxiv · Jul 26, 2019 · PreprintGenomics