Herta Ademi

Ovarian development is driven by early spatiotemporal priming of the coelomic epithelium

This study shows that ovarian cellular diversity arises from spatially organized, transcriptionally heterogeneous coelomic epithelium progenitors in fetal mouse and human ovaries, which are primed toward supporting or steroidogenic identities.

Expression of Wnt5a defines the major progenitors of fetal and adult Leydig cells

This study identifies Wnt5a as a marker for steroidogenic progenitors that give rise to fetal and adult Leydig cells and peritubular myoid cells in the mouse testis.

Leveraging biobank-scale rare and common variant analyses to identify ASPHD1 as the main driver of reproductive traits in the 16p11.2 locus

The paper identifies ASPHD1 as a key driver of reproductive traits in the 16p11.2 locus using biobank data, Mendelian randomization, and animal models.