Altered tau in rTg4510 mice after a single interfaced CHIMERA traumatic brain injury
Wai Hang Cheng, Honor Cheung, Amy Kang, Jianjia Fan, Jennifer Gradi Cooper, Mehwish Anwer, Carlos Barrón, Anna Wilkinson, Grace Hu, Jefferey Yue, Peter A. Cripton, David J. Vocadlo, Cheryl Lea Wellington
This study examines the effects of a single moderate-severe TBI in rTg4510 mice using CHIMERA, finding divergent tauopathy and autophagolysosome responses in surviving mice.
bioRxiv · Sep 1, 2022 · PreprintNeuroscience